|
| Status |
Public on Aug 24, 2015 |
| Title |
Nkx2.2, Nkx6.1, Olig2, and Gli3 genomic binding regions in neural progenitors [ChIP-Seq] |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
Nkx2.2, Nkx6.1, and Olig2 are transcriptional repressors regulating somatic motor neuron and interneuron subtypes in neural progenitors. The purpose of this study was to identify their target genes and to elucidate their gene regulatory mechanisms, including their relationship to Sonic Hedgehog/Gli pathway.
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| Overall design |
Nkx2.2, Nkx6.1, Olig2, and Gli3 binding profiles were determined by ChIP-seq in neural progenitors derived in vitro from mouse embryonic stem cells
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| |
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| Contributor(s) |
Nishi Y, McMahon AP |
| Citation(s) |
26293298 |
| Submission date |
Sep 23, 2014 |
| Last update date |
May 15, 2019 |
| Contact name |
Yuichi Nishi |
| E-mail(s) |
yuichi.nishi@gmail.com
|
| Phone |
323-442-8077
|
| Organization name |
University of Southern California
|
| Department |
Eli and Edythe Broad-CIRM Center for Regenerative Medicine
|
| Lab |
Andrew McMahon
|
| Street address |
1425 San Pablo St.
|
| City |
Los Angeles |
| State/province |
CA |
| ZIP/Postal code |
90033 |
| Country |
USA |
| |
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| Platforms (3) |
| GPL9250 |
Illumina Genome Analyzer II (Mus musculus) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (13)
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| This SubSeries is part of SuperSeries: |
| GSE65462 |
Nkx2.2, Nkx6.1, Olig2, and Gli3 genomic binding regions and overexpression in neural progenitors |
|
| Relations |
| BioProject |
PRJNA261806 |
| SRA |
SRP047421 |
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