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| Status |
Public on Sep 27, 2014 |
| Title |
Gene expression profiles in the heart tissues of heart-specific Bmal1 knockout mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Mice without cardiac Bmal1 function develop severe progressive heart failure with age. To examine the mechanism underlying the failing heart phenotype observed in heart-specific Bmal1 knockout mice, microarray analyses were performed. The analyses revealed that broad classes of genes regulating cellular energy metabolism were upregulated or downregulated in the heart tissues of heart-specific Bmal1 knockout mice compared with those of control animals.
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| Overall design |
Heart total RNA extracted from six animals per genotype (control and heart-specific Bmal1 knockout) was pooled and then used for a microarray analysis.
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| Contributor(s) |
Kohsaka A |
| Citation(s) |
25389966 |
| Submission date |
Sep 26, 2014 |
| Last update date |
Jul 19, 2017 |
| Contact name |
Akira Kohsaka |
| Organization name |
Wakayama Medical University
|
| Department |
Physiology
|
| Street address |
811-1, Kimiidera
|
| City |
Wakayama |
| ZIP/Postal code |
641-8509 |
| Country |
Japan |
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| Platforms (1) |
| GPL13912 |
Agilent-028005 SurePrint G3 Mouse GE 8x60K Microarray (Feature Number version) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA262134 |
