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Series GSE62333 Query DataSets for GSE62333
Status Public on Feb 17, 2015
Title Transcriptomic profiles of skin fibroblasts from patients affected by schizophrenia and controls
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Whole-genome expression studies in peripheral tissues of patients affected by schizophrenia (SCZ) can provide new insights into the molecular basis of the disorder and innovative biomarkers that may be of great usefulness in the clinical practice. Recent evidence suggests that skin fibroblasts could represent a non-neural peripheral model useful to investigate molecular alterations in psychiatric disorders.
A microarray expression study was conducted comparing transcriptomic profiles of skin fibroblasts from SCZ patients and controls. Fibroblasts can be more advantageous to discover mental disorder aetiological mechanisms since they seem more similar to neurons and less affected by the environmental confounders.
 
Overall design Transcriptomic profiles of human skin fibroblasts obtained from 20 schizophrenia patients were compared to 20 controls
 
Contributor(s) Cattane N, Minelli A, Milanesi E, Maj C, Bignotti S, Bortolomasi M, Bocchio-Chiavetto L, Gennarelli M
Citation(s) 25658856
Submission date Oct 14, 2014
Last update date Nov 08, 2016
Contact name Nadia Cattane
E-mail(s) ncattane@fatebenefratelli.it
Organization name University of Brescia
Department Department of Translational and Molecular Medicine
Street address Viale Europa 11
City Brescia
State/province BS
ZIP/Postal code 25123
Country Italy
 
Platforms (1)
GPL11532 [HuGene-1_1-st] Affymetrix Human Gene 1.1 ST Array [transcript (gene) version]
Samples (40)
GSM1525415 Human_fibroblast_C1
GSM1525416 Human_fibroblast_C2
GSM1525417 Human_fibroblast_C3
Relations
BioProject PRJNA263840

Download family Format
SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE62333_RAW.tar 167.1 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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