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| Status |
Public on Oct 22, 2014 |
| Title |
SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Characterization of the selectivity of SMN splicing modifiers in SMA type I fibroblasts by RNASeq
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| Overall design |
In total 12 samples were analyzed, divided into four distinct groups (treated with SMN-C3 @ 500 nM; controls for SMN-C3; treated with SMN-C1 @ 100 nM; controls for SMN-C1) containing 3 replicates each.
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| Contributor(s) |
Dakka A, Ghosh A, Turpoff A, Bhattacharyya A, Furia B, Lee C, Ko C, Haehnke D, Welch EM, Metzger F, Karp GM, Chen G, Ratni H, Qi H, Gerlach I, Narasimhan J, Mull JL, Ma J, Babiak J, Colacino JM, Sheedy J, Ling KK, Chen KS, McCarthy KD, Rubin LL, Eng LA, Santarelli L, Sivaramakrishnan M, Weetall M, Ebeling M, Woll MG, Lynes MS, Zhang N, Almstead NG, Risher N, Naryshkin NA, Trifillis P, Fontoura P, Vazirani P, Schmucki R, Kong R, Paushkin SV, Peltz SW, Gabbeta V, Zhang X, Zhao X, Moon Y, Feng Z |
| Citation(s) |
25104390 |
| Submission date |
Oct 21, 2014 |
| Last update date |
May 15, 2019 |
| Contact name |
Friedrich Metzger |
| Organization name |
F. Hoffmann-La Roche
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| Street address |
Grenzacherstr.
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| City |
Basel |
| ZIP/Postal code |
CH-4070 |
| Country |
Switzerland |
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| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA264368 |
| SRA |
SRP049090 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE62540_RAW.tar |
950.0 Kb |
(http)(custom) |
TAR (of TXT) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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