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| Status |
Public on Feb 10, 2015 |
| Title |
RNA-Seq Versus Oligonucleotide Array Assessment of Dose-Dependent TCDD-elicited Hepatic Gene Expression in Mice [Array] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Dose-dependent hepatic gene expression was examined following repeated exposure (every 4 days for 28 days) to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). These data were used to examine the effect of repeated TCDD exposure as well as compare the performance of RNA-Seq and Agilent oligonucleotide microarrays for detection and identificatioin of differentially expressed genes.
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| Overall design |
Three biological replicates for each dose (0.01, 0.03, 0.1, 0.3, 1, 3, 10, 30) of TCDD and sesame oil vehicle
This submission represents the Agilent microarrays component of study.
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| |
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| Contributor(s) |
Nault R, Fader KA, Zacharewski TR |
| Citation(s) |
25958198 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| P42 ES004911 |
Project 3: TCDD-Elicited Steatosis: The Role of Aryl Hydrocarbon Receptor |
MICHIGAN STATE UNIVERSITY |
Timothy R. Zacharewski |
|
| Submission date |
Oct 30, 2014 |
| Last update date |
Jan 12, 2017 |
| Contact name |
Rance Nault |
| E-mail(s) |
naultran@msu.edu
|
| Organization name |
Michigan State University
|
| Department |
Institute for Integrative Toxicology
|
| Street address |
1129 Farm Ln
|
| City |
East Lansing |
| State/province |
United States |
| ZIP/Postal code |
48824 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL7202 |
Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version) |
|
| Samples (48)
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| This SubSeries is part of SuperSeries: |
| GSE62903 |
RNA-Seq Versus Oligonucleotide Array Assessment of Dose-Dependent TCDD-elicited Hepatic Gene Expression in Mice |
|
| Relations |
| BioProject |
PRJNA265838 |
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