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Status |
Public on Apr 12, 2015 |
Title |
Expression data from Pin1 inhibitor ATRA and Pin1 knockdown |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
ATRA was identified as a Pin1 inhibitor via fluorescence polarization-based high throughput screening. We performed microarray expression profiling to demonstrate the similarity between ATRA and Pin1 KD at the genome-wide level
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Overall design |
APL NB4 cells in response to ATRRA or inducible Pin1 knockdown for 3 days were collected for RNA extraction and hybridization on Affymetrix microarrays. We sought to validate in genome-wide level whether similarity occurred between ATRA and Pin1 knockdown-treated NB4 cells.
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Contributor(s) |
Wei S, Nehama M, Bruno-Joseph MG, Hu H, Luo M, Lu KP |
Citation(s) |
25849135 |
Submission date |
Nov 06, 2014 |
Last update date |
Oct 29, 2018 |
Contact name |
Kun Ping Lu |
Organization name |
Beth Israel Deaconess Medical Center
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Street address |
330 Brookline Ave
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City |
Boston |
State/province |
MA |
ZIP/Postal code |
02215 |
Country |
USA |
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Platforms (1) |
GPL17586 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
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Samples (4)
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Relations |
BioProject |
PRJNA266532 |