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Series GSE63059 Query DataSets for GSE63059
Status Public on Apr 12, 2015
Title Expression data from Pin1 inhibitor ATRA and Pin1 knockdown
Organism Homo sapiens
Experiment type Expression profiling by array
Summary ATRA was identified as a Pin1 inhibitor via fluorescence polarization-based high throughput screening. We performed microarray expression profiling to demonstrate the similarity between ATRA and Pin1 KD at the genome-wide level
 
Overall design APL NB4 cells in response to ATRRA or inducible Pin1 knockdown for 3 days were collected for RNA extraction and hybridization on Affymetrix microarrays. We sought to validate in genome-wide level whether similarity occurred between ATRA and Pin1 knockdown-treated NB4 cells.
 
Contributor(s) Wei S, Nehama M, Bruno-Joseph MG, Hu H, Luo M, Lu KP
Citation(s) 25849135
Submission date Nov 06, 2014
Last update date Oct 29, 2018
Contact name Kun Ping Lu
Organization name Beth Israel Deaconess Medical Center
Street address 330 Brookline Ave
City Boston
State/province MA
ZIP/Postal code 02215
Country USA
 
Platforms (1)
GPL17586 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
Samples (4)
GSM1539076 1.NB4-VEC
GSM1539077 2.NB4-TETON.377
GSM1539078 3.NB4-DMSO
Relations
BioProject PRJNA266532

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE63059_RAW.tar 105.7 Mb (http)(custom) TAR (of CEL, CHP)
Processed data included within Sample table
Processed data provided as supplementary file

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