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| Status |
Public on Nov 15, 2015 |
| Title |
MLL5 orchestrates a cancer self-renewal state by repressing the histone variant H3.3 and globally reorganizing chromatin [methylation] |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by genome tiling array
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| Summary |
Genome wide DNA methylation profiling of fourteen adult GBM primary cultures and their comparison to pediatric GBMs [GSE36278; GSE55712]
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| Overall design |
Bisulphite converted DNA from fourteen adult GBM primary cultures were hybridised to the Illumina 450k Human Methylation Beadchip
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| Contributor(s) |
Gallo M, Vanner R, Coutinho FJ, Gayden T, Remke M, Li R, Mack SC, Desai K, Lee L, Lan X, Park N, Sturm D, Barsyte D, Smil D, Kushida M, Head R, Clarke ID, Arrowsmith C, Pfister S, Taylor MD, Jabado N, Bazett-Jones DP, Lupien M, Dirks PB |
| Citation(s) |
26626085 |
| Submission date |
Nov 13, 2014 |
| Last update date |
Mar 22, 2019 |
| Contact name |
Peter B Dirks |
| Organization name |
The Hospital for Sick Children
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| Department |
Developmental and Stem Cell Biology
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| Street address |
555 University Avenue
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| City |
Toronto |
| State/province |
Ontario |
| ZIP/Postal code |
M5G 1X8 |
| Country |
Canada |
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| Platforms (1) |
| GPL13534 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482) |
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| Samples (14)
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| GSM1544782 |
genomic DNA from aGBM primary culture 1 |
| GSM1544783 |
genomic DNA from aGBM primary culture 2 |
| GSM1544784 |
genomic DNA from aGBM primary culture 3 |
| GSM1544785 |
genomic DNA from aGBM primary culture 4 |
| GSM1642624 |
genomic DNA from aGBM primary culture 5 |
| GSM1642625 |
genomic DNA from aGBM primary culture 6 |
| GSM1642626 |
genomic DNA from aGBM primary culture 7 |
| GSM1642627 |
genomic DNA from aGBM primary culture 8 |
| GSM1642628 |
genomic DNA from aGBM primary culture 9 |
| GSM1642629 |
genomic DNA from aGBM primary culture 10 |
| GSM1642630 |
genomic DNA from aGBM primary culture 11 |
| GSM1642631 |
genomic DNA from aGBM primary culture 12 |
| GSM1642632 |
genomic DNA from aGBM primary culture 13 |
| GSM1642633 |
genomic DNA from aGBM primary culture 14 |
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| Relations |
| BioProject |
PRJNA267120 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE63267_RAW.tar |
296.4 Mb |
(http)(custom) |
TAR (of IDAT) |
| GSE63267_non-normalized_data.txt.gz |
33.4 Mb |
(ftp)(http) |
TXT |
| Processed data included within Sample table |
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