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Series GSE6482 Query DataSets for GSE6482
Status Public on Jan 01, 2007
Title mECK36: a cell and animal model of virally induced Kaposi's sarcoma
Organism Mus musculus
Experiment type Expression profiling by array
Summary Transfection of a Kaposi's sarcoma (KS) herpesvirus (KSHV) Bacterial Artificial Chromosome (KSHVBac36) into mouse bone marrow endothelial lineage cells generated a cell (mECK36) that induced KS-like tumors in mice. mECK36 formed KSHV-harboring vascularized spindle-cell sarcomas that were LANA+ and displayed a KSHV and host transcriptomes reminiscent of KS tumors.
Keywords: Cell type comparison
Overall design There are three biological replicates per sample. Tumors (mKS) were compared the the human KS signature. mECK36 and mEC-V were compared to putative BM lineage cells.
Contributor(s) Mesri E, Cavallin L
Citation(s) 17349582, 22746102
Submission date Dec 07, 2006
Last update date Feb 11, 2019
Contact name Enrique Mesri
Phone 305-243-5659
Organization name University of Miami
Department Microbiology and Immunology
Street address 1550 NW 10th Ave, PAP-109B
City Miami
State/province FL
ZIP/Postal code 33136
Country USA
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (9)
GSM149222 mECK36 1
GSM149223 mECK36 2
GSM149224 mECK36 3
BioProject PRJNA98727

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Supplementary file Size Download File type/resource
GSE6482_RAW.tar 33.1 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file

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