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Series GSE6485 Query DataSets for GSE6485
Status Public on Dec 06, 2007
Title Expression data from olfactory epithelium of Harlequin mutant mice compared to littermate controls
Organism Mus musculus
Experiment type Expression profiling by array
Summary Microarray analysis of gene expression in the olfactory epithelium of Harlequin mouse as a model of oxidative-stress induced neurodegeneration of olfactory sensory neurons
Keywords: comparison of gene expression level in unperturbed tissue of mutant vs. control mouse
Overall design Olfactory epithelium from Harlequin mutant mice and littermate control mice was microdissected for RNA extraction and hybridization on Affymetrix microarrays. We compared levels of gene expression in 6-month old mice to begin to identify mechanisms of oxidative-stress induced neurodegeneration and to correlate the cellular changes that we observed in the olfactory epithelium by using histology and immunohistochemistry with gene expression changes.
Contributor(s) Vaishnav RA, Getchell ML, Huang L, Hersh MA, Stromberg AJ, Getchell TV
Citation(s) 17868149
Submission date Dec 08, 2006
Last update date Feb 11, 2019
Contact name Marilyn L. Getchell
Organization name University of Kentucky
Department Anatomy and Neurobiology
Lab Sanders-Brown Center on Aging
Street address 800 South Limestone St.
City Lexington
State/province KY
ZIP/Postal code 40536-0230
Country USA
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (6)
GSM149360 6 month old adult male mutant mouse Hq/Y, biol rep1
GSM149361 6 month old adult male mutant mouse Hq/Y, biol rep2
GSM149362 6 month old adult male mutant mouse Hq/Y, biol rep3
BioProject PRJNA98731

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SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE6485_RAW.tar 23.4 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file

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