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Series GSE64919 Query DataSets for GSE64919
Status Public on May 13, 2015
Title Genes regulated in EML1 cells expressing the TEL-AML1 oncogene after 5 and 7 days of treatment with IL7 and FLT3 ligand.
Organism Mus musculus
Experiment type Expression profiling by array
Summary The t(12;21) translocation is the most common genetic rearrangement in childhood acute lymphoblastic leukemia (ALL) and gives rise to the TEL-AML1 fusion gene, which functions as a transcription factor.
TEL-AML1 expression in EML1 cells results in an impairment of differentiation along the B-lymphoid lineage.
Overall design We analyzed gene expression profiles of EML1 cells after expression of TEL-AML1
Contributor(s) Alcalay M
Citation(s) 25893288
Submission date Jan 13, 2015
Last update date Apr 18, 2017
Contact name Myriam Alcalay
Organization name European Institute of Oncology
Department Experimental Oncology
Lab Functional Genomics
Street address Via Adamello 16
City Milan
ZIP/Postal code 20139
Country Italy
Platforms (1)
GPL11533 [MoGene-1_1-st] Affymetrix Mouse Gene 1.1 ST Array [transcript (gene) version]
Samples (12)
GSM1583299 EML1 infected with the empty pWPI lentiviral vector - rep 1
GSM1583300 EML1 infected with the empty pWPI lentiviral vector - rep 2
GSM1583301 EML1 infected with the empty pWPI lentiviral vector treated with IL7 and FLT3L for 5 days- rep 1
BioProject PRJNA272512

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE64919_RAW.tar 52.4 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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