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Series GSE66346 Query DataSets for GSE66346
Status Public on Mar 10, 2015
Title Expression data from renal cancer xenograft tumor treated with sunitinib or vehicle
Organism Homo sapiens
Experiment type Expression profiling by array
Summary We established 3 types of primary xenograft models (KURC;Kyoto University Renal Cancer-1,2,3) derived from human renal cell carcinoma tissues, and 40 mg/day of sunitinib was orally administered.
We performed microarray analysis to compare the gene expression profile of sunitinib-treated primary xenograft tumors (sensitive or resistant status) with that of vehicle-treated.
Overall design Total RNA was extracted from KURC1,2,3 xenograft tumors treated with sunitinib or vehicle. Forty mg/day of sunitinib was orally administered once a day, and KURC1 and KURC3 developed resistance to sunitinib.
Contributor(s) Shibasaki N
Citation(s) 26114873
Submission date Feb 26, 2015
Last update date Jul 26, 2018
Contact name Shibasaki Noboru
Organization name Kyoto University
Department Urology
Street address 54 Shogoinkawahara-cho Sakyo-ku
City Kyoto
ZIP/Postal code 606-8561
Country Japan
Platforms (1)
GPL6244 [HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Samples (9)
GSM1620057 KURC1 vehicle#1
GSM1620058 KURC1 vehicle#2
GSM1620059 KURC1 sunitinib-sensitive#1
BioProject PRJNA276577

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MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE66346_RAW.tar 38.2 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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