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| Status |
Public on Apr 01, 2015 |
| Title |
Expression data from prostate cancer cell lines LNCap (androgen dependent) and DU145 (androgen independent), transfected with Pin1 or control siRNA |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Pin1 inhibiton exerts anti-oncogenic effects on LNCaP and DU145 cells despite the gene regulation patterns by Pin1 were different in both cells.
We investigated how Pin1 modulates the gene expressions in the androgen-dependent as well as the androgen-independent prostate cancer cell lines
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| Overall design |
For the knockdown of human Pin1, the siRNAs against Pin1 (Pin1 shRNA-1: 5’-CGGCAACAGCAGCAGUGGUGGCAAA-3’ and Pin1 shRNA-2: 5’-GCCCUGGAGCUGAUCAACGGCUACA-3’) and control siRNA were purchased from Invitrogen (Stealth/siRNA duplex oligoribonucleotides)
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| Contributor(s) |
Kushiyama A, Kanaoka R, Asano T |
| Citation(s) |
26039047 |
| Submission date |
Mar 31, 2015 |
| Last update date |
Jul 26, 2018 |
| Contact name |
Akifumi Kushiyama |
| E-mail(s) |
a-kushiyama@asahi-life.or.jp
|
| Phone |
+81-3-3639-5501
|
| Organization name |
The Institute for Adult Diseases, Asahi Life Foundation
|
| Street address |
2-2-6, Nihonbashi Bakurocho, Chuo-ku
|
| City |
Tokyo |
| ZIP/Postal code |
103-0002 |
| Country |
Japan |
| |
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| Platforms (1) |
| GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA279982 |
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