|
| Status |
Public on Dec 01, 2015 |
| Title |
Affymetrix SNP array data for chronic myelomonocytic leukemia samples |
| Organism |
Homo sapiens |
| Experiment type |
Genome variation profiling by SNP array
|
| Summary |
Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic disorder with heterogeneous clinical, morphological and genetic characteristics. Clonal cytogenetic abnormalities are found in 20-30% of patients with CMML. Patients with low risk cytogenetic features (normal karyotype and isolated loss of Y chromosome) account for approximately 80% of CMML patients and often fall into the low risk categories of CMML prognostic scores. SNP-A were performed in 82 CMML patients with low risk karyotypes and uninformative results for conventional G-banding cytogenetics (CC).
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| |
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| Overall design |
Affymetrix SNP arrays were performed according to the manufacturer's directions on DNA extracted from bone marrow or peripheral blood samples.
Copy number analysis of Affymetrix array was performed for 82 CMML samples at diagnosis or prior to any treatment,
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| |
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| Contributor(s) |
Palomo L, Solé F, Zamora L |
| Citation(s) |
26509444 |
| Submission date |
Mar 31, 2015 |
| Last update date |
Nov 27, 2018 |
| Contact name |
Laura Palomo |
| Organization name |
Josep Carreras Leukemia Research Institute
|
| Department |
Campus ICO-GTiP
|
| Lab |
MDS Group
|
| Street address |
Carretera de Can Ruti, Camí de les Escoles, s/n
|
| City |
Barcelona |
| State/province |
Barcelona |
| ZIP/Postal code |
08916 |
| Country |
Spain |
| |
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| Platforms (2) |
| GPL6801 |
[GenomeWideSNP_6] Affymetrix Genome-Wide Human SNP 6.0 Array |
| GPL16131 |
[CytoScanHD_Array] Affymetrix CytoScan HD Array |
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| Samples (82)
|
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| Relations |
| BioProject |
PRJNA279998 |
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