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| Status |
Public on Apr 02, 2015 |
| Title |
Unraveling the rat blood genome-wide transcriptome after oral administration of Lavender oil by a two-color dye-swap DNA microarray approach |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
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| Summary |
Lavender oil (LO) is commonly used oil in aromatherapy, with well-defined volatile components linalool and linalyl acetate, in non-traditional medicine. To understand and demonstrate the potential positive effects of LO on the body, we have established an animal model for investigating the orally administered LO effects genome-wide in the rat tissues. In this data submission, we investigate the effect of LO ingestion in the blood. These results are the first such inventory of genes that are affected by lavender essential oil (LO) in the blood of an animal model, forming the basis for further functional analysis and investigation.
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| Overall design |
Briefly, rats were administered LO at 5 mg/kg (usual therapeutic dose in humans) followed by screening of differentially expressed genes in the tissues, using a 4×44-K whole-genome rat chip (Agilent microarray platform; Agilent Technologies, Palo Alto, CA, USA) in conjunction with a dye-swap approach.
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| Contributor(s) |
Hori M, Kubo H, Shibato J, Saito T, Ogawa T, Shioda S, Rakwal R |
| Citation(s) |
27330992 |
| Submission date |
Apr 01, 2015 |
| Last update date |
Dec 21, 2016 |
| Contact name |
RANDEEP RAKWAL |
| E-mail(s) |
plantproteomics@gmail.com
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| Phone |
+81-(0)90-1853-7875
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| Organization name |
University of Tsukuba
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| Department |
Institute of Health and Sport Sciences
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| Lab |
GSI 403
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| Street address |
1-1-1 Tennodai
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| City |
Tsukuba |
| State/province |
Ibaraki |
| ZIP/Postal code |
305-8574 |
| Country |
Japan |
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| Platforms (1) |
| GPL4135 |
Agilent-014879 Whole Rat Genome Microarray 4x44K G4131F (Feature Number version) |
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| Samples (2) |
| GSM1648085 |
Control (Cy3) x Lavender Oil Blood (Cy5) |
| GSM1648086 |
Control (Cy5) x Lavender Oil Blood (Cy3) |
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| Relations |
| BioProject |
PRJNA280089 |
