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Series GSE67651 Query DataSets for GSE67651
Status Public on May 07, 2015
Title Expression data from fatty acid and bile acid receptor agonist treated liver sinusoidal endothelial cells
Organism Mus musculus
Experiment type Expression profiling by array
Summary Liver sinusoidal endothelial cells (LSEC) are unique endothelial cell typelining the sinusoids of the liver and we have shown that these cells respond in a unique matter when exposed to saturated and unsaturated free fatty acids (FFA) and bile acids.
We used microarray to analyze the transcriptional differences between the LSEC exposed to free fatty acids and bile acid receptor agonists to further shed light on their role in non-alcoholic fatty liver disease.
 
Overall design The Murine Liver Sinusoidal Endothelial Cell Line (TSEC) was treated with palmitic and oleic acid or the bile acid receptor agonist INT-767 for 8 hours. Total RNA was then harvested to determine transcriptional differences.
 
Contributor(s) McMahan RH, Porsche C, Edwards MG, Rosen HR
Citation(s) 27454769
Submission date Apr 07, 2015
Last update date Jun 27, 2019
Contact name Michael Edwards
E-mail(s) michael.edwards@ucdenver.edu
Phone 303-724-6054
Organization name UC Denver
Department Pulmonary
Street address 12700 East 19th Avenue, Box C272
City Aurora
State/province CO
ZIP/Postal code 80045
Country USA
 
Platforms (1)
GPL16570 [MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array [transcript (gene) version]
Samples (12)
GSM1652806 TSEC Media- biological rep1
GSM1652807 TSEC Media- biological rep2
GSM1652808 TSEC Media- biological rep3
Relations
BioProject PRJNA280542

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE67651_RAW.tar 111.6 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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