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Series GSE6875 Query DataSets for GSE6875
Status Public on Jan 26, 2007
Title Development of Regulatory T cell Precursors in the Absence of a Functional Foxp3 Protein
Organism Mus musculus
Experiment type Expression profiling by array
Summary To analyze gene expression in in regulatory T cell precursors that develop in the absence of a functional Foxp3 protein as compared to that of normal regulatory T cells
Keywords: Cell type comparison
Overall design Murine wild-type and mutant (delta) Foxp3 alleles were tagged with EGFP reporters. CD4 positive T cells expressing the respective tagged Foxp3 allele (Foxp3/EGFP and delta Foxp3/EGFP) were isolated from hemizygous male mice by cell sorting using FACS. CD4 positive cells that did not express the EGFP tag were a isolated. Total RNA was prepared and used in the array studies.
Contributor(s) Lin W, Haribhai D, Reland LM, Truong N, Carlson MR, Williams CB, Chatila TA
Citation(s) 17273171
Submission date Jan 25, 2007
Last update date Feb 11, 2019
Contact name Marc Richard John Carlson
Organization name UCLA
Department Department of Human Genetics
Lab Stan Nelson Laboratory
Street address 695 Charles E. Young Dr. S.
City Los Angeles
State/province CA
ZIP/Postal code 90095
Country USA
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (8)
GSM158519 76090_CD4+, FoxP3(EGFP-) mouse cells
GSM158520 76091_CD4+, FoxP3(EGFP+) mouse cells
GSM158521 76092_CD4+, (delta)FoxP3(EGFP-) mouse cells
BioProject PRJNA99127

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE6875_RAW.tar 29.2 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file

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