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Series GSE68849 Query DataSets for GSE68849
Status Public on Feb 01, 2016
Title Impact of influenza A on human plasmacytoid dendritic cells (pDC) gene expression
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Over 2600 genes were differentially expressed in pDCs exposed to influenza A compared with the controls (no virus). Multiple functional group clusters of genes were impacted, including those involving antiviral responses and also metabolism, such as the glycolysis, oxidative phosphorylation, glucose metabolic process, and positive regulation of macromolecule biosynthesis clusters.
 
Overall design Blood pDCs were purified from 5 human donors, exposed ex vivo for 8 h to either influenza A or no virus, harvested, and RNA was extracted for subsequent DNA microarray analysis.
 
Contributor(s) Bajwa G, Gill MA
Citation(s) 26826244
Submission date May 13, 2015
Last update date Aug 13, 2018
Contact name Michelle Ann Gill
Organization name University of Texas Southwestern Medical Center
Department Pediatrics
Street address 5323 Harry Hines Blvd
City Dallas
ZIP/Postal code 75390
Country USA
 
Platforms (1)
GPL10558 Illumina HumanHT-12 V4.0 expression beadchip
Samples (10)
GSM1684095 Donor 1 - No virus control - 8h
GSM1684096 Donor 1 - Influenza treated - 8h
GSM1684097 Donor 2 - No virus control - 8h
Relations
BioProject PRJNA283884

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE68849_RAW.tar 26.2 Mb (http)(custom) TAR
GSE68849_non-normalized.txt.gz 5.6 Mb (ftp)(http) TXT
Processed data included within Sample table
Raw data are available on Series record

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