GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE6945 Query DataSets for GSE6945
Status Public on Feb 22, 2007
Title The Retinoblastoma Binding Protein RBP2 is an H3K4 demethylase
Organism Mus musculus
Experiment type Expression profiling by array
Summary The roles of histone demethylase RBP2 in gene expression were assessed using gene expression profiling experiments with wild type and RBP2-/- primary MEFs. Several cytokine genes including SDF1 and Kit ligand were upregulated upon inactivation of RBP2.
Keywords: mouse embryonic fibroblasts, gene expression profiling, microarray, Affymetrix Mouse Genome 430 2.0, cell type comparison
Overall design Total RNA were extracted from two independent lines of wild type and RBP2 primary MEFs at passage 3 and analyzed for gene expression profiles using Affymetrix platform.
Contributor(s) Klose RJ, Yan Q, Tothova Z, Yamane K, Erdjument-Bromage H, Tempst P, Gilliland DG, Zhang Y, Kaelin WG
Citation(s) 17320163
Submission date Feb 02, 2007
Last update date Feb 11, 2019
Contact name Qin Yan
Phone 2037856672
Organization name Yale School of Medicine
Street address Department of Pathology, PO Box 208023
City New Haven
State/province CT
ZIP/Postal code 06614
Country USA
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (4)
GSM160088 wild type MEF(1)
GSM160104 wild type MEF(2)
GSM160105 RBP2-/- MEF(1)
BioProject PRJNA99331

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE6945_RAW.tar 14.9 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap