|
| Status |
Public on Jun 12, 2016 |
| Title |
Recurrent alterations of TNFAIP3 (A20) in T-cell large granular lymphocytic leukemia |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We identified a novel recurrent genetic lesion in T-LGL. Mutations of the tumour suppressor gene TNFAIP3 causing amino-acid exchanges or protein truncations were seen in 3/39 cases (8%).
|
| |
|
| Overall design |
RNA sequencing (Illumina HiSeq 2500) of 5 index patients with paired tumor and non-tumor samples.
|
| |
|
| Contributor(s) |
Klein-Hitpass L, Johansson P |
| Citation(s) |
26199174 |
| Submission date |
Jun 10, 2015 |
| Last update date |
May 15, 2019 |
| Contact name |
Ludger Klein-Hitpass |
| E-mail(s) |
ludger.klein-hitpass@uni-essen.de
|
| Phone |
+49 201 723 85552
|
| Organization name |
Institut fuer Zellbiologie
|
| Department |
Universitaetsklinikum
|
| Lab |
BioChip Lab
|
| Street address |
Virchowstr. 173
|
| City |
Essen |
| ZIP/Postal code |
D-45122 |
| Country |
Germany |
| |
|
| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
|
| Samples (10)
|
|
| Relations |
| BioProject |
PRJNA286292 |
| SRA |
SRP059322 |
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