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| Status |
Public on Aug 27, 2015 |
| Title |
Expression data from Bone marrow and Fetal liver Lineage-c-Kit+Sca-1+ (LSK) cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Loss of polycomb-group gene Ezh2 causes activation of fetal gene signature in adult mouse bone marrow (BM) hematopoietic stem and progenitor cells (HSPCs). Ezh2 directly represses fetal-specific let-7 target genes, including Lin28, thereby cooperates with let-7 microRNAs in silencing fetal gene signature in BM HSPCs.
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| Overall design |
We purified Lineage-Sca-1+c-Kit+ (LSK) HSPCs from E14.5 FL and adult BM and subjected them to microarray analysis.
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| Contributor(s) |
Iwama A, Oshima M |
| Citation missing |
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| Submission date |
Jun 10, 2015 |
| Last update date |
Feb 02, 2018 |
| Contact name |
Motohiko Oshima |
| E-mail(s) |
oshima@faculty.chiba-u.jp
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| Phone |
+81432262187
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| Organization name |
Chiba University
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| Street address |
1-8-1 Inohana
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| City |
Chiba |
| State/province |
State... |
| ZIP/Postal code |
260-8670 |
| Country |
Japan |
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| Platforms (1) |
| GPL10787 |
Agilent-028005 SurePrint G3 Mouse GE 8x60K Microarray (Probe Name version) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA286674 |
