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| Status |
Public on Oct 01, 2015 |
| Title |
2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) Alters Lipid Metabolism and Depletes Immune Cell Populations in the Jejunum of C57BL/6 Mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Dose-dependent jejunal epithelial gene expression was examined following repeated exposure (every 4 days for 28 days) to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). These data were used to examine the effect of repeated TCDD exposure on jejunal differential gene expression, in order to investigate the role of the jejunum in TCDD-elicited steatohepatitis in C57BL/6.
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| Overall design |
Three biological replicates for each dose (0.01, 0.03, 0.1, 0.3, 1, 3, 10, 30) of TCDD and sesame oil vehicle
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| Contributor(s) |
Fader KA, Nault R, Ammendolia DA, Harkema JR, Williams KJ, Crawford RB, Kaminski NE, Potter D, Sharratt B, Zacharewski TR |
| Citation(s) |
26377647 |
| Submission date |
Jun 29, 2015 |
| Last update date |
Jan 12, 2017 |
| Contact name |
Timothy Zacharewski |
| Organization name |
Michigan State University
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| Department |
BMB
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| Lab |
Zacharewski
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| Street address |
603 Wilson Road
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| City |
East Lansing |
| State/province |
Michigan |
| ZIP/Postal code |
48824 |
| Country |
USA |
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| Platforms (1) |
| GPL7202 |
Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version) |
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| Samples (48)
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| Relations |
| BioProject |
PRJNA288588 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE70379_RAW.tar |
254.9 Mb |
(http)(custom) |
TAR (of GPR) |
| Processed data included within Sample table |
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