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Series GSE7079 Query DataSets for GSE7079
Status Public on Dec 11, 2007
Title Chronic rat exposure to cigarette smoke
Organism Rattus norvegicus
Experiment type Expression profiling by array
Summary Chronic obstructive pulmonary disease is a smoking-related disease that lacks effective therapies due partly to the poor understanding of disease pathogenesis. The aim of this study was to identify molecular pathways which could be responsible for the damaging consequences of smoking. To do this, we employed recently described bioinformatic methods to analyze differences in global gene expression, which we then related to the pathological changes induced by cigarette smoke (CS). Sprague-Dawley rats were exposed to whole-body CS for 1 day and for various periods up to 8 months.
Keywords: Timecourse
Overall design Timecourse with 12 timepoints with 8 replicates at each time point.
Citation(s) 17720875
Submission date Feb 20, 2007
Last update date Feb 21, 2017
Contact name Christopher S Stevenson
Organization name Novartis Institutes for BioMedical Research
Department Respiratory Diseases
Street address Wimblehurst Road
City Horsham
ZIP/Postal code RH12 5AB
Country United Kingdom
Platforms (1)
GPL85 [RG_U34A] Affymetrix Rat Genome U34 Array
Samples (209)
GSM170276 Day 1 control 1
GSM170277 Day 1 smoke exposure 1
GSM170278 Day 3 control 1
BioProject PRJNA98491

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE7079_RAW.tar 397.9 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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