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| Status |
Public on Aug 08, 2015 |
| Title |
Transgenic overexpression of Pla2g2f at a level relevant to skin pathology display alopecia and psoriasis-like epidermal hyperplasia |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Pla2g2f is dominantly expressed in the suprabasal layer of mouse epidermis. Microarray gene profiling supported the overall tendency of epidermal and sebaceous gland hyperplasia as well as alopecia in Pla2g2f-transgenic skin.
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| Overall design |
Pla2g2f-Tg/+ mice and littermate controls (C57BL/6 background); 25-day old; skin; pooled from 4 mice for each genotype.
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| Contributor(s) |
Yamamoto K, Nishito Y, Murakami M |
| Citation(s) |
26438362 |
| Submission date |
Aug 07, 2015 |
| Last update date |
Nov 02, 2015 |
| Contact name |
Kei Yamamoto |
| Organization name |
Tokyo Metropolitan Institute of Medical Science
|
| Department |
Lipid Metabolism Project
|
| Street address |
2-1-6 kamikitazawa
|
| City |
Setagaya |
| State/province |
Tokyo |
| ZIP/Postal code |
156-8506 |
| Country |
Japan |
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| Platforms (1) |
| GPL2872 |
Agilent-012694 Whole Mouse Genome G4122A (Feature Number version) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA292158 |
