 |
 |
GEO help: Mouse over screen elements for information. |
|
| Status |
Public on Aug 06, 2018 |
| Title |
mRNA Expression data from murine hearts subjected to ligation of the left anterior descending coronary artery (myocardial infarction, MI model) or sham surgery (SH) |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
The left anterior descending coronary artery permanent ligation model of myocardial infarction was used to study the time of day differences in genetic responses post-MI between sleep-time MI, wake-time MI, wake-sham and sleep-sham mouse hearts.
The micorarray approach allows the investigation of gene expression changes of all genes in sleep-time MI vs. wake-time MI vs. sham hearts.
|
| |
|
| Overall design |
There are a total of 12 samples, 6 from cardiovascular disease MI and 6 from normal SHAM hearts collected 8 hours after surgery. Specifically for MI: There were 3 mice sacrificed 8 hours after wake-time MI as biological replicates, and there were 3 mice sacrificed 8 hours after sleep-time MI as biological replicates. Specifically for SHAM: There were 3 mice sacrificed 8 hours after wake-time SH as biological replicates, and there were 3 mice sacrificed 8 hours after sleep-time SH as biological replicates.
|
| |
|
| Contributor(s) |
Martino TA |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Aug 10, 2015 |
| Last update date |
Aug 07, 2018 |
| Contact name |
Elena Tsimakouridze |
| E-mail(s) |
etsimako@uoguelph.ca
|
| Organization name |
University of Guelph
|
| Street address |
50 Stone Rd E
|
| City |
Guelph |
| ZIP/Postal code |
N1G 2W1 |
| Country |
Canada |
| |
|
| Platforms (1) |
| GPL8321 |
[Mouse430A_2] Affymetrix Mouse Genome 430A 2.0 Array |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA292432 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE71906_RAW.tar |
25.0 Mb |
(http)(custom) |
TAR (of CEL, CHP) |
| Processed data included within Sample table |
| Processed data provided as supplementary file |
|
|
|
|
 |
Less...
More...