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| Status |
Public on Aug 27, 2015 |
| Title |
Expression data from HaCaT cells stimulated by IL-22 |
| Platform organisms |
Homo sapiens; synthetic construct |
| Sample organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
Non-coding RNA profiling by array
|
| Summary |
Psoriasis is an inflammatory skin disease and the exact pathogenesis has not been fully illuminated yet. It has been demonstrated that interleukin-22 (IL-22) plays a significant role in the pathogenesis of psoriasis.
Our study aimed to explore the role of IL-22 and its target miRNAs in pathogenesis of psoriasis.
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| Overall design |
Differentially expressed miRNAs and mRNAs in HaCaT cells with IL-22 stimulation were analysed through miRNA and mRNA microarrays. qRT-PCR assay was conducted to validate microarrays results.
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| Contributor(s) |
Sun Q, Jiang M |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Aug 26, 2015 |
| Last update date |
Mar 15, 2019 |
| Contact name |
Meng Jiang |
| E-mail(s) |
1037447134@qq.com
|
| Phone |
15066142801
|
| Organization name |
Qilu hospital
|
| Street address |
lixia street
|
| City |
Jinan |
| State/province |
Shandong |
| ZIP/Postal code |
250012 |
| Country |
China |
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| Platforms (2) |
| GPL16686 |
[HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [transcript (gene) version] |
| GPL19117 |
[miRNA-4] Affymetrix Multispecies miRNA-4 Array |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA293946 |
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