|
| Status |
Public on Dec 01, 2015 |
| Title |
Skeletal muscle gene expression after high-fat diet with or without endothelial-directed deletion of FoxO |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
In a murine model of high-fat diet, Mx1-Cre was used to induce knockdown of forkhead box O 1,3 and 4 (FoxO 1,3 and 4) in the endothelium of adult mice. Skeletal muscle gene-expression was assessed after 8 weeks of high-fat diet in wild type versus FoxO knockdown mice.
|
| |
|
| Overall design |
Total RNA isolated from gastrocnemius muscle after 8 weeks of high-fat diet in male FVB/n mice harbouring an endothelial directed deletion of FoxO1/3/4 (Mx1-Cre+);FoxO1,3,4L/L) (n=8) and corresponding MxCre-;FoxO1,3,4L/L littermates (n=8).
|
| |
|
| Contributor(s) |
Rullman E, Haas T |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Sep 01, 2015 |
| Last update date |
Feb 21, 2018 |
| Contact name |
Eric Rullman |
| E-mail(s) |
eric.rullman@gmail.com
|
| Phone |
+46858586777
|
| Organization name |
Karolinska Institutet
|
| Department |
Laboratory Medicine
|
| Lab |
Clinical Physiology
|
| Street address |
C1:82 Karolinska University Hospital, Huddinge
|
| City |
Stockholm |
| ZIP/Postal code |
14186 |
| Country |
Sweden |
| |
|
| Platforms (1) |
| GPL16570 |
[MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array [transcript (gene) version] |
|
| Samples (16)
|
|
| Relations |
| BioProject |
PRJNA294386 |
Less...
More...