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Series GSE7258 Query DataSets for GSE7258
Status Public on Feb 20, 2008
Title Expression data of bronchoalveolar lavage cells from control or urethane treated AJ mice
Organism Mus musculus
Experiment type Expression profiling by array
Summary AJ mouse is susceptible to lung carcinogenesis from urethane treatment and is a good model for human adenocarcinoma. We completed a study using microarray analysis of bronchoalveolar lavage cells from control or urethane treated mice. A unique macrophage expression signature in the lung tumor microenvironment was able to correctly classify the lavage samples.
Keywords: AJ mouse control and urethane treatment carcinogenesis protocol
 
Overall design RNA from bronchoalveolar lavage cells of age matched untreated AJ mice controls (C) or from urethane treated (T) AJ mice was prepared. Datasets were accurately classified using a unique macrophage gene expression signature derived from the tumor microenvironment.
 
Contributor(s) Stearman RS, Nield LD, Grady MC, Malkinson AM, Geraci MW
Citation(s) 18172294
Submission date Mar 13, 2007
Last update date Feb 11, 2019
Contact name Robert S Stearman
E-mail(s) Robert.Stearman@uchsc.edu
Phone 303-315-2317
Fax 303-315-5632
Organization name UCHSC
Department Medicine/Pulmonary
Lab Stearman
Street address 4200 E Ninth Ave
City Denver
State/province CO
ZIP/Postal code 80262
Country USA
 
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (17)
GSM174895 C6_C13 BAL Normal Control
GSM174896 C14 BAL Normal Control
GSM174897 C33 BAL Normal Control
This SubSeries is part of SuperSeries:
GSE7269 AJ mouse lung carcinogenesis study
Relations
BioProject PRJNA104071

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE7258_RAW.tar 60.5 Mb (http)(custom) TAR (of CEL, EXP)
Raw data provided as supplementary file
Processed data included within Sample table

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