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Series GSE7280 Query DataSets for GSE7280
Status Public on May 18, 2007
Title Gene expression in peripheral cells: effects of Foxp3 and PDE3B
Organism Mus musculus
Experiment type Expression profiling by array
Summary This data set is comprised of all peripheral (pooled lymph nodes and spleen) T cell subsets presented in this manuscript. These include T-N, T-25, T-FN and T-R cells; T-25, T-FN and T-R cells from mice treated with IL-2; and T-R cells transduced with empty, PDE3B-expressing or PDE3B(H801A)-expressing retroviral vectors (after transfer into recipient mice).
Keywords: cell type comparison, response to growth factor, genetic modification
Overall design Detailed methods are presented in the manuscript and in the attached Supplementary Information. All RNA samples were derived from cells immediately after isolation from mice. Although this data set is comprised of 2 separate experiments (cells isolated from normal mice or IL-2 treated mice and cells transduced with retroviral vectors and passaged through recipient mice), the 10 expression arrays were normalized together to allow for cross comparison.
Contributor(s) Gavin MA, Rasmussen JP, Fontenot JD, Vasta V, Manganiello VC, Beavo JA, Rudensky AY
Citation(s) 17220874
Submission date Mar 15, 2007
Last update date Feb 11, 2019
Contact name Alexander Rudensky
Organization name University of Washington
Department Immunology
Street address 1959 Pacific St
City Seattle
State/province WA
ZIP/Postal code 98195
Country USA
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (10)
GSM154499 GFP- CD25- CD4+ cells from Foxp3(gfp/gfp) mice
GSM154500 GFP- CD25+ CD4+ cells from Foxp3(gfp/gfp) mice
GSM154501 GFP+ CD4+ cells from Foxp3(gfpko/wt) mice
This SubSeries is part of SuperSeries:
GSE7773 Foxp3-dependent programme of regulatory T-cell differentiation
BioProject PRJNA105509

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE7280_RAW.tar 33.0 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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