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| Status |
Public on Jul 01, 2007 |
| Title |
Candida-induced expression profile in HUVEC |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Using oligonucleotide microarray analysis, we identified 56 genes that were transcriptionally up-regulated and 69 that were suppressed upon exposure of endothelial cells to C. albicans. Among the regulated genes those attributed to the categories ‘chemotaxis’, ‘signaling’, and ‘transcription and translation’ were remarkably overrepresented.
Keywords: endothelial stress response
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| |
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| Overall design |
We performed 4 independent experiments comparing the expression profiles of untreated HUVEC monolayer with those of candida-infected HUVEC monolayer.
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| |
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| Contributor(s) |
Müller V, Viemann D, Schmidt M, Endres N, Ludwig S, Leverkus M, Roth J, Goebeler M |
| Citation(s) |
18056390 |
| Submission date |
Mar 23, 2007 |
| Last update date |
Aug 10, 2018 |
| Contact name |
Dorothee Viemann |
| E-mail(s) |
Viemann.Dorothee@mh-hannover.de
|
| Phone |
+49-511-532 - 7823
|
| Organization name |
Hannover Medical School
|
| Department |
Department of Pediatric Pulmonology, Allergy and Neonatology
|
| Street address |
Carl-Neuberg-Straße 1
|
| City |
Hannover |
| State/province |
Deutschland |
| ZIP/Postal code |
30625 |
| Country |
Germany |
| |
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| Platforms (1) |
| GPL96 |
[HG-U133A] Affymetrix Human Genome U133A Array |
|
| Samples (8)
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| Relations |
| BioProject |
PRJNA100425 |
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