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Series GSE7357 Query DataSets for GSE7357
Status Public on Mar 22, 2008
Title Expression data from Hfe-deficient liver and duodenum in mouse strains with differing susceptibilities to iron loading
Organism Mus musculus
Experiment type Expression profiling by array
Summary Hfe disruption in the mouse leads to experimental hemochromatosis by a mechanism which remains elusive. Evidence for at least five modifier genes has been obtained. These account for the higher iron load of Hfe-deficient D2 mice compared to B6 mice. Gene expression profling was used to clarify the mechanism of Hfe action and to identify potential modifier genes.
Keywords: response to genetic modification
Overall design Liver and duodenum were obtained from wild-type and Hfe-deficient B6 and D2 mice (three mice per strain/genotype combination).
Contributor(s) Roth M, Coppin H
Citation(s) 17945001
Submission date Mar 23, 2007
Last update date Feb 11, 2019
Contact name Marie-Paule Roth
Phone 33 5 62744508
Fax 33 5 62744558
Organization name Inserm
Department U563
Lab Génétique
Street address Chu Purpan
City Toulouse
ZIP/Postal code 31024
Country France
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (24)
GSM177149 Liver-B6WT-Biological rep1
GSM177150 Liver-B6WT-Biological rep2
GSM177151 Liver-B6WT-Biological rep3
BioProject PRJNA100429

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE7357_RAW.tar 87.1 Mb (http)(custom) TAR (of CEL, CHP, EXP)
Raw data provided as supplementary file
Processed data provided as supplementary file

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