|
| Status |
Public on Dec 17, 2015 |
| Title |
MLL-rearranged acute lymphoblastic leukemias upregulate BCL-2 through H3K79 methylation and are highly sensitive to the BCL-2 specific antagonist ABT-199 |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We present ChIP-seq in the t(4;11) cell line SEM for different components of the MLL-AF4 complex as well as other chromatin proteins
|
| |
|
| Overall design |
Examination of 5 histone marks, MLL, AF4, ENL and CFP1 in t(4;11) cells
|
| |
|
| Contributor(s) |
Milne TA, Kerry J |
| Citation(s) |
26711339 |
| Submission date |
Nov 09, 2015 |
| Last update date |
May 15, 2019 |
| Contact name |
Thomas Milne |
| E-mail(s) |
thomas.milne@imm.ox.ac.uk
|
| Organization name |
Weatherall Institute of Molecular Medicine
|
| Department |
Molecular Haematology Unit
|
| Street address |
John Radcliffe Hospital
|
| City |
Oxford |
| ZIP/Postal code |
OX3 9DS |
| Country |
United Kingdom |
| |
|
| Platforms (3) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
| Samples (14)
|
|
| Relations |
| BioProject |
PRJNA301600 |
| SRA |
SRP065960 |
Less...
More...