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| Status |
Public on Apr 12, 2007 |
| Title |
Expression data from rat lung alveolar development |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
|
| Summary |
Lung alveolarization is a complex process that involves interactions between several cell types and leads to considerable increase in gas-exchange surface area. The step designated secondary septation includes elastogenesis from interstitial fibroblasts.
We used microarrays to detail the global programme of fibroblast gene expression that underly secondary septation, and identified numerous genes that undergo signficant changes in expression
Keywords: Time course
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| Overall design |
Rat lung fibroblats were extemporaneously isolated at successive stages of postnatal development that flank the septation period for RNA extraction and hybridization on Affymetrix microarrays. Three biological replicates from three different litters were prepared for each time point.
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| |
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| Contributor(s) |
Boucherat O, Bourbon JR |
| Citation(s) |
17911382 |
| Submission date |
Apr 10, 2007 |
| Last update date |
Jul 31, 2017 |
| Contact name |
Jacques Bourbon |
| E-mail(s) |
jacques.bourbon@creteil.inserm.fr
|
| Phone |
00 33 1 49 81 37 33
|
| Fax |
00 33 1 49 98 37 33
|
| Organization name |
Université de Paris 12
|
| Department |
Faculté de Médecine
|
| Street address |
8 rue du Général Sarrail
|
| City |
Créteil |
| ZIP/Postal code |
94000 |
| Country |
France |
| |
|
| Platforms (1) |
| GPL1355 |
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array |
|
| Samples (9)
|
| GSM181524 |
postnatal day 2, biological repl1 (litter 1) |
| GSM181525 |
postnatal day 2, biological repl2 (litter 2) |
| GSM181526 |
postnatal day 2, biological repl3 (litter 3) |
| GSM181527 |
postnatal day 7, biological repl1 (litter 1) |
| GSM181528 |
postnatal day 7, biological repl2 (litter 2) |
| GSM181529 |
postnatal day 7, biological repl3 (litter 3) |
| GSM181530 |
postnatal day 21, biological repl1 (litter 1) |
| GSM181531 |
postnatal day 21, biological repl2 (litter 2) |
| GSM181532 |
postnatal day 21, biological repl3 (litter 3) |
|
| Relations |
| BioProject |
PRJNA100313 |
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