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Status |
Public on Nov 13, 2016 |
Title |
Endometrial transcriptome profile of cows affected by subclinical or clinical endometritis |
Organism |
Bos taurus |
Experiment type |
Expression profiling by array
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Summary |
Clinical or subclinical endometritis could affect the cow fertility by disturbing the molecular milieu of the uterine environment. We used a global gene expression approach to understand the effect of clinical and subclinical endometritis on endometrial transcriptome profiles of cows
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Overall design |
Holstein Friesian cows at 42-60 days postpartum were classified as healthy (HE), subclinical endometritis (SE) or clinical endometritis (CE) based on clinical examination of the animals and histological evaluation of the corresponding endometrial biopsies. Endometrial transcriptome profile changes and associated molecular pathways induced by subclinical or clinical endometritis were then investigated using GeneChip® Bovine Genome Array.
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Contributor(s) |
Salilew-Wondim D, Ibrahim S, Gebremedhn S, Tesfaye D, Heppelmann M, Bollwein H, Pfarrer C, Tholen E, Neuhoff C, Schellander K, Hoelker M |
Citation missing |
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Submission date |
Nov 13, 2015 |
Last update date |
Nov 15, 2016 |
Contact name |
Dessie Salilew-Wondim |
E-mail(s) |
dsalilew@uni-bonn.de
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Organization name |
University of Bonn
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Department |
Animal breeding and husbandry group
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Street address |
Endenicher Allee 15
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City |
Bonn |
State/province |
NRW |
ZIP/Postal code |
D-53115 |
Country |
Germany |
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Platforms (1) |
GPL2112 |
[Bovine] Affymetrix Bovine Genome Array |
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Samples (8)
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GSM1939785 |
Endometrial samples from healthy cows (HE) rep1 |
GSM1939786 |
Endometrial samples from healthy cows (HE) rep2 |
GSM1939787 |
Endometrial samples from clinical endometritis cows (CE) rep1 |
GSM1939788 |
Endometrial samples from clinical endometritis cows (CE) rep2 |
GSM1939789 |
Endometrial samples from clinical endometritis cows (CE) rep3 |
GSM1939790 |
Endometrial samples from sub clinical endometritis cows (SE) rep1 |
GSM1939791 |
Endometrial samples from sub clinical endometritis cows (SE)rep 2 |
GSM1939792 |
Endometrial samples from sub clinical endometritis cows (SE) rep 3 |
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Relations |
BioProject |
PRJNA302124 |