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Series GSE7568 Query DataSets for GSE7568
Status Public on May 15, 2008
Title Effects of TGF-beta on mature macrophages
Organism Homo sapiens
Experiment type Expression profiling by array
Summary The goal of the study was to identify the effects of TGF-beta on primary human macrophages maturated under different conditions.
Keywords: time course, differentiation conditions, alternative activation
 
Overall design For the analysis of TGF-beta effects macrophages were differentiated in the presence of IL-4 or IL-4 in combination with dexamethasone. After 5 days differentiation mature macrophages were stimulated by TGF-beta for 24 hours. In the case of IL-4/dexamethasone stimulation an additional data point was taken. In this case macrophages were also stimulated by TGF-beta for 3 hours. For every group 5 independent donors were taken.
 
Contributor(s) Gratchev A, Kzhyshkowska J
Citation(s) 18453574
Submission date Apr 22, 2007
Last update date Jul 15, 2019
Contact name Alexei Gratchev
E-mail(s) alexei.gratchev@haut.ma.uni-heidelberg.de
Phone 0621 3833103
Organization name Medical Centre Mannheim, University of Heidelberg
Department Department of Dermatology
Street address
City Mannheim
ZIP/Postal code 68167
Country Germany
 
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (25)
GSM183165 Macrophages IL-4 - control BC348.1
GSM183193 Macrophages IL-4 - control BC348.3
GSM183196 Macrophages IL-4 - control BC349.4
Relations
BioProject PRJNA100337

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE7568_RAW.tar 520.1 Mb (http)(custom) TAR (of CEL, CHP)
Processed data provided as supplementary file
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