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Series GSE7640 Query DataSets for GSE7640
Status Public on Jul 15, 2008
Title Gene expression profile induced by moderate physical exercise in heart left ventricles in rats
Organism Rattus norvegicus
Experiment type Expression profiling by array
Summary Physical exercise training is a known protective factor against cardiovascular morbidity and mortality. Nevertheless, the underlying specific molecular mechanisms still remain uncompletely explored. To identify molecular mechanisms by which exercise training induces this favorable phenotype a genomic approach was used in an animal model of mild exercise previously demonstrated by our group to induce cardioprotection.
Our data indicate that mild exercise by inducing no or few permanent changes in gene expression profile is able to determine cardioprotection without induction of cardiac hypertrophy.
Keywords: Case-Control: Response to physical exsercise
Overall design We investigated the gene expression profile by Affymetrix technology (230 2.0 GeneChip rat genome array) induced by mild exercise training (treadmill running: 25 m/min, 10% incline, 1 h/day, 3 days/week, 10 weeks) on left ventricle (LV) of exercise-trained (n=10) and sedentary control (n=10) rats.
Contributor(s) Giusti B, Rossi L, Lapini I, Magi A, Veicsteinas A, Marini M, Samaja M, Abbate R
Citation(s) 19643001
Submission date Apr 26, 2007
Last update date Jul 31, 2017
Contact name Betti Giusti
Organization name University of Florence
Department Dpt. of Medical and Surgical Critical Care
Street address viale Morgagni, 85
City Florence
ZIP/Postal code 50134
Country Italy
Platforms (1)
GPL1355 [Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Samples (20)
GSM184851 Sedentary rat 1
GSM184852 Sedentary rat 2
GSM184853 Sedentary rat 3
BioProject PRJNA99775

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE7640_RAW.tar 45.8 Mb (http)(custom) TAR (of CEL, CHP)
Raw data provided as supplementary file
Processed data provided as supplementary file

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