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| Status |
Public on May 22, 2016 |
| Title |
Identification of Novel Changes in Human Skeletal Muscle Proteome following Roux-en-Y Gastric Bypass Surgery |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
The mechanisms of metabolic improvements following Roux-en-Y gastric bypass (RYGB) surgery are not entirely clear. Therefore, the aim of our study was to investigate the role of obesity and RYGB on the human skeletal muscle proteome.
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| Overall design |
Basal muscle biopsies were obtained from seven obese (BMI >40 kg/m2) female subjects (45.1±3.6 years) pre- and 3 months post-RYGB, and euglycemic-hyperinsulinemic clamps were used to assess insulin sensitivity.
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| |
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| Contributor(s) |
Coletta DK |
| Citation(s) |
27207528 |
| Submission date |
Jan 03, 2016 |
| Last update date |
Jan 09, 2018 |
| Contact name |
Dawn K Coletta |
| E-mail(s) |
dcoletta@deptofmed.arizona.edu
|
| Phone |
520-626-9316
|
| Organization name |
UNIVERSITY OF ARIZONA
|
| Department |
Medicine
|
| Street address |
1501 N. Campbell Ave
|
| City |
Tucson |
| State/province |
AZ |
| ZIP/Postal code |
85724 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL17077 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version) |
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| Samples (14)
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| Relations |
| BioProject |
PRJNA307520 |
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