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Series GSE76719 Query DataSets for GSE76719
Status Public on Jan 12, 2016
Title Gene expression data from lung of mice infected with H5N1 or H1N1 virus
Organism Mus musculus
Experiment type Expression profiling by array
Summary To find the different host response during H5N1 and H1N1 infection, we have employed whole genome microarray expression profiling as a discovery platform to identify genes differentially expressed in mouse lungs infected by H5N1 and H1N1 virus. BALB/c mice were infected with live H5N1 virus , live H1N1 virus, or inactivated H5N1 virus or allantoic fluid (AF) for 24 h.
 
Overall design Mice were intra-tracheally inoculated with 106 TCID50 of live H5N1 virus or an identical volume of inactivated H5N1 virus , 106 TCID50 of live H1N1 virus, or allantoic fluid (AF). After 24 hours, lungs were taken for RNA extraction and hybridization on Agilent microarrays.H5N1 and H1N1 virus induced gene expression in mouse was measured. This experiment was performed with 3 mice in each group.
 
Contributor(s) Zhang Y, Tang J, Yang N, Sun Y, Jiang C
Citation(s) 27354218
Submission date Jan 11, 2016
Last update date Jan 12, 2017
Contact name Yanli Zhang
Organization name Chinese Academy of Medical Sciences, Peking Union Medical College
Lab State Key Laboratory of Medical Molecular Biology
Street address No.5 Dongdansantiao
City Beijing
State/province BEIJING
ZIP/Postal code 100005
Country China
 
Platforms (1)
GPL7202 Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version)
Samples (5)
GSM2036540 Lung_live H1N1_24hr_rep1
GSM2036541 Lung_live H5N1_24hr_rep1
GSM2036542 Lung_AF1_24hr_rep1
Relations
BioProject PRJNA308453

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE76719_RAW.tar 32.2 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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