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| Status |
Public on Oct 01, 2007 |
| Title |
Transcriptional Profiling of Cerebral Malaria |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Cerebral malaria (CM) is a leading cause of death in the world. Better understanding of the pathogenesis of this disease is critical for the development of novel therapies. In this work, we investigated temporal gene expression profiles in the brains of CM-susceptible and CM-resistant mice during infection with P. Berghia ANKA (PbA).
In this model of CM, susceptible mice develop neurological signs by day 6 post infection while resistant mice do not develop neurological manifestations during malarial infection.
Keywords: Time course
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| Overall design |
C57/B6 (CM-susceptible) and Balb/C (CM-resistant) mice were infected with PbA. Gene expression profiles from whole brains were obtained at day 0 (uninfected), day 1, day 3, and day 6.
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| Contributor(s) |
Gharib SA, Lovegrove F |
| Citation(s) |
17991715 |
| Submission date |
May 15, 2007 |
| Last update date |
Oct 19, 2022 |
| Contact name |
Sina Gharib |
| E-mail(s) |
sagharib@uw.edu
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| Organization name |
University of Washington
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| Department |
Medicine
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| Street address |
850 Republican St.
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| City |
Seattle |
| State/province |
WA |
| ZIP/Postal code |
98109 |
| Country |
USA |
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| Platforms (1) |
| GPL8321 |
[Mouse430A_2] Affymetrix Mouse Genome 430A 2.0 Array |
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| Samples (64)
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| GSM189596 |
B6 day 0, biological rep 1, tech rep 1 |
| GSM189597 |
B6 day 0, biological rep 1, tech rep 2 |
| GSM189598 |
B6 day 0, biological rep 2, tech rep 1 |
| GSM189599 |
B6 day 0, biological rep 2, tech rep 2 |
| GSM189600 |
B6 day 0, biological rep 3, tech rep 1 |
| GSM189601 |
B6 day 0, biological rep 3, tech rep 2 |
| GSM189602 |
B6 day 0, biological rep 4, tech rep 1 |
| GSM189603 |
B6 day 0, biological rep 4, tech rep 2 |
| GSM189604 |
B6 day 1, biological rep 1, tech rep 1 |
| GSM189605 |
B6 day 1, biological rep 1, tech rep 2 |
| GSM189606 |
B6 day 1, biological rep 2, tech rep 1 |
| GSM189607 |
B6 day 1, biological rep 2, tech rep 2 |
| GSM189608 |
B6 day 1, biological rep 3, tech rep 1 |
| GSM189609 |
B6 day 1, biological rep 3, tech rep 2 |
| GSM189610 |
B6 day 1, biological rep 4, tech rep 1 |
| GSM189611 |
B6 day 1, biological rep 4, tech rep 2 |
| GSM189612 |
B6 day 3, biological rep 1, tech rep 1 |
| GSM189613 |
B6 day 3, biological rep 1, tech rep 2 |
| GSM189614 |
B6 day 3, biological rep 2, tech rep 1 |
| GSM189615 |
B6 day 3, biological rep 2, tech rep 2 |
| GSM189616 |
B6 day 3, biological rep 3, tech rep 1 |
| GSM189617 |
B6 day 3, biological rep 3, tech rep 2 |
| GSM189618 |
B6 day 3, biological rep 4, tech rep 1 |
| GSM189619 |
B6 day 3, biological rep 4, tech rep 2 |
| GSM189620 |
B6 day 6, biological rep 1, tech rep 1 |
| GSM189621 |
B6 day 6, biological rep 1, tech rep 2 |
| GSM189622 |
B6 day 6, biological rep 2, tech rep 1 |
| GSM189623 |
B6 day 6, biological rep 2, tech rep 2 |
| GSM189624 |
B6 day 6, biological rep 3, tech rep 1 |
| GSM189625 |
B6 day 6, biological rep 3, tech rep 2 |
| GSM189626 |
B6 day 6, biological rep 4, tech rep 1 |
| GSM189627 |
B6 day 6, biological rep 4, tech rep 2 |
| GSM189628 |
Balb/c day 0, biological rep 1, tech rep 1 |
| GSM189629 |
Balb/c day 0, biological rep 1, tech rep 2 |
| GSM189630 |
Balb/c day 0, biological rep 2, tech rep 1 |
| GSM189631 |
Balb/c day 0, biological rep 2, tech rep 2 |
| GSM189632 |
Balb/c day 0, biological rep 3, tech rep 1 |
| GSM189633 |
Balb/c day 0, biological rep 3, tech rep 2 |
| GSM189634 |
Balb/c day 0, biological rep 4, tech rep 1 |
| GSM189635 |
Balb/c day 0, biological rep 4, tech rep 2 |
| GSM189636 |
Balb/c day 1, biological rep 1, tech rep 1 |
| GSM189637 |
Balb/c day 1, biological rep 1, tech rep 2 |
| GSM189638 |
Balb/c day 1, biological rep 2, tech rep 1 |
| GSM189639 |
Balb/c day 1, biological rep 2, tech rep 2 |
| GSM189640 |
Balb/c day 1, biological rep 3, tech rep 1 |
| GSM189641 |
Balb/c day 1, biological rep 3, tech rep 2 |
| GSM189642 |
Balb/c day 1, biological rep 4, tech rep 1 |
| GSM189643 |
Balb/c day 1, biological rep 4, tech rep 2 |
| GSM189644 |
Balb/c day 3, biological rep 1, tech rep 1 |
| GSM189645 |
Balb/c day 3, biological rep 1, tech rep 2 |
| GSM189646 |
Balb/c day 3, biological rep 2, tech rep 1 |
| GSM189647 |
Balb/c day 3, biological rep 2, tech rep 2 |
| GSM189648 |
Balb/c day 3, biological rep 3, tech rep 1 |
| GSM189649 |
Balb/c day 3, biological rep 3, tech rep 2 |
| GSM189650 |
Balb/c day 3, biological rep 4, tech rep 1 |
| GSM189651 |
Balb/c day 3, biological rep 4, tech rep 2 |
| GSM189652 |
Balb/c day 6, biological rep 1, tech rep 1 |
| GSM189653 |
Balb/c day 6, biological rep 1, tech rep 2 |
| GSM189654 |
Balb/c day 6, biological rep 2, tech rep 1 |
| GSM189655 |
Balb/c day 6, biological rep 2, tech rep 2 |
| GSM189656 |
Balb/c day 6, biological rep 3, tech rep 1 |
| GSM189657 |
Balb/c day 6, biological rep 3, tech rep 2 |
| GSM189658 |
Balb/c day 6, biological rep 4, tech rep 1 |
| GSM189659 |
Balb/c day 6, biological rep 4, tech rep 2 |
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| Relations |
| BioProject |
PRJNA100039 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE7814_RAW.tar |
129.6 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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