|
| Status |
Public on Apr 05, 2016 |
| Title |
H3K4me3 ChIP in multiple myeloma MM1S cells in the presence and absence of KDM5-C70 |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
In this experiment we demonstrate the use of an inhibitor of the KDM5 family of histone demethylases, KDM5-C70, on H3K4me3 marks in the multiple myeloma cell line MM1S. KDM5-C70 increases H3K4me3 in a global fashion across the genome.
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| |
|
| Overall design |
Examination of H3K4me3 mark across MM1S cells treated with either KDM5-C70 or vehicle control
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| |
|
| Contributor(s) |
Oppermann U, Hookway E |
| Citation(s) |
27214403 |
| Submission date |
Feb 23, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Udo Oppermann |
| Organization name |
University of Oxford
|
| Department |
Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences
|
| Street address |
Botnar Research Centre, Nuffield Orthopaedic Centre, Windmill Road
|
| City |
Oxford |
| State/province |
Oxfordshire |
| ZIP/Postal code |
OX3 7LD |
| Country |
United Kingdom |
| |
|
| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
| Samples (8)
|
|
| Relations |
| BioProject |
PRJNA312929 |
| SRA |
SRP070701 |
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