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| Status |
Public on Mar 08, 2016 |
| Title |
Screening of differentially expressed genes after IMB5046 treatment |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
To investigate the effects of IMB5046 treatment on cells, we used the gene expression microarray to compare the difference between the IMB5046-treated cells and control cells. A431 cells were treated with 100 nM IMB5046 or 0.1% DMSO (vehicle) for 24 hr. A total of 441 genes were down-regulated and 383 genes were up-regulated by at least 2-fold between IMB5046-treated and control cells.The most obviuos changes in Gene Ontology biolocial process classification were related to cell death and immune response.
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| Overall design |
A431 cells were treated with 100 nM IMB5046 or (0.1% DMSO) vehicle for 24 h. Then, total RNA was extracted from cells using TRIzol reagent and analyzed.
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| Contributor(s) |
Zheng Y |
| Citation(s) |
27510727 |
| Submission date |
Mar 07, 2016 |
| Last update date |
Apr 02, 2020 |
| Contact name |
Yanbo Zheng |
| E-mail(s) |
zhengyb2001@sina.com
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| Organization name |
Institute of Medicinal Biotechnology
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| Street address |
1# Tiantan Xili
|
| City |
Beijing |
| ZIP/Postal code |
100050 |
| Country |
China |
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| Platforms (1) |
| GPL13497 |
Agilent-026652 Whole Human Genome Microarray 4x44K v2 (Probe Name version) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA314485 |
