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| Status |
Public on Mar 31, 2019 |
| Title |
Investigation of Bach2 function by heme-iron homeostasis in red-pulp macrophage. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Macrophages are central in regulating iron homeostasis. Transcription repressor Bach2 regulates by heme. Here we investigated the relationship between heme-regulated Bach2 and macrophage in spleen. We found that gene expression were not many change between WT and Bach2 knock out mice in red-pulp macrophage.Our results suggest that the function of the red-pulp macrophage is not dependent on according to expression of Bach2.
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| Overall design |
Gene expression in red-pulp macrophages cells of WT and Bach2 KO mice was measured. 3 independent mice ware used for each genotype.
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| Contributor(s) |
Watanabe-Matsui M, Igarashi K |
| Citation missing |
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| Submission date |
Mar 31, 2016 |
| Last update date |
Apr 02, 2019 |
| Contact name |
Kazuhiko Igarashi |
| E-mail(s) |
igarashi@med.tohoku.ac.jp
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| Phone |
+81227177597
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| Organization name |
Tohoku University
|
| Street address |
Seiryo 2-1
|
| City |
Sendai |
| ZIP/Postal code |
980-8575 |
| Country |
Japan |
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| Platforms (1) |
| GPL13912 |
Agilent-028005 SurePrint G3 Mouse GE 8x60K Microarray (Feature Number version) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA317152 |
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