|
| Status |
Public on Aug 31, 2007 |
| Title |
Age-related transcriptional changes and the effect of dietary supplementation of vitamin E in the mouse heart |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
To investigate the global effects of vitamin E supplementation on heart aging, we used high-density oligonucleotide arrays to measure transcriptional alterations in 30-month-old B6C3F1 mice supplemented with α- and γ-tocopherol since middle age (15 months).
Keywords: expression profiling
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| Overall design |
Gene expression profiles were obtained from 5-month-old controls, 30-month-old controls and 30-month-old mice supplemented with α-tocopherol (1g/kg), or a mixture of α- and γ-tocopherol (500mg/kg of each tocopherol).
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| |
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| Contributor(s) |
Park S, Page GP, Kim K, Allison DB, Meydani M, Weindruch R, Prolla TA |
| Citation(s) |
17316780 |
| Submission date |
Jun 15, 2007 |
| Last update date |
Feb 18, 2018 |
| Contact name |
Sang-Kyu Park |
| E-mail(s) |
sangkyu@colorado.edu
|
| Phone |
303-492-5159
|
| Fax |
303-492-8063
|
| Organization name |
University of Colorado at Boulder
|
| Department |
IBG
|
| Street address |
1480 30th St.
|
| City |
Boulder |
| State/province |
CO |
| ZIP/Postal code |
80303 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL81 |
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array |
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| Samples (20)
|
| GSM201736 |
Mouse young heart C5-Ht-4 |
| GSM201737 |
Mouse young heart C5-Ht-5 |
| GSM201741 |
Mouse old heart C30-Ht-1 |
| GSM201753 |
Mouse old heart C30-Ht-2 |
| GSM201767 |
Mouse old heart C30-Ht-3 |
| GSM201768 |
Mouse old heart C30-Ht-4 |
| GSM201770 |
Mouse old heart C30-Ht-5 |
| GSM201772 |
Mouse old heart w/ a-tocopherol aT-Ht-1 |
| GSM201773 |
Mouse old heart w/ a-tocopherol aT-Ht-2 |
| GSM201775 |
Mouse old heart w/ a-tocopherol aT-Ht-3 |
| GSM201777 |
Mouse old heart w/ a-tocopherol aT-Ht-4 |
| GSM201778 |
Mouse old heart w/ a-tocopherol aT-Ht-5 |
| GSM201780 |
Mouse old heart w/ a- & g-tocopherol agT-Ht-1 |
| GSM201782 |
Mouse old heart w/ a- & g-tocopherol agT-Ht-2 |
| GSM201784 |
Mouse old heart w/ a- & g-tocopherol agT-Ht-3 |
| GSM201786 |
Mouse old heart w/ a- & g-tocopherol agT-Ht-4 |
| GSM201788 |
Mouse old heart w/ a- & g-tocopherol agT-Ht-5 |
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| This SubSeries is part of SuperSeries: |
| GSE8162 |
Age-related transcriptional changes and the effect of dietary supplementation of vitamin E in the mouse heart and brain |
|
| Relations |
| BioProject |
PRJNA105413 |
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