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Status |
Public on Aug 31, 2007 |
Title |
Age-related transcriptional changes and the effect of dietary supplementation of vitamin E in the mouse brain |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
We established the transcriptional profile of brain aging and examine the global effects of vitamin E supplementation on age-related alterations in expression in the aged mouse brain. Keywords: expression profiling
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Overall design |
Gene expression profiles were obtained from the neocortex tissues of 5-month-old controls, 30-month-old controls and 30-month old B6C3F1 mice with middle age-onset supplementation of α-tocopherol or a mixture of α- and γ-tocopherol (500mg/kg of each tocopherol).
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Contributor(s) |
Park S, Page GP, Kim K, Allison DB, Meydani M, Weindruch R, Prolla TA |
Citation(s) |
17316780 |
Submission date |
Jun 15, 2007 |
Last update date |
Feb 11, 2019 |
Contact name |
Sang-Kyu Park |
E-mail(s) |
sangkyu@colorado.edu
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Phone |
303-492-5159
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Fax |
303-492-8063
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Organization name |
University of Colorado at Boulder
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Department |
IBG
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Street address |
1480 30th St.
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City |
Boulder |
State/province |
CO |
ZIP/Postal code |
80303 |
Country |
USA |
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Platforms (1) |
GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
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Samples (20)
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GSM201794 |
Mouse young brain C5-Br-4 |
GSM201795 |
Mouse young brain C5-Br-5 |
GSM201796 |
Mouse old brain C30-Br-1 |
GSM201797 |
Mouse old brain C30-Br-2 |
GSM201799 |
Mouse old brain C30-Br-3 |
GSM201801 |
Mouse old brain C30-Br-4 |
GSM201802 |
Mouse old brain C30-Br-5 |
GSM201804 |
Mouse old brain w/ a-tocopherol aT-Br-1 |
GSM201805 |
Mouse old brain w/ a-tocopherol aT-Br-2 |
GSM201806 |
Mouse old brain w/ a-tocopherol aT-Br-3 |
GSM201808 |
Mouse old brain w/ a-tocopherol aT-Br-4 |
GSM201809 |
Mouse old brain w/ a-tocopherol aT-Br-5 |
GSM201811 |
Mouse old brain w/ a- & g-tocopherol agT-Br-1 |
GSM201812 |
Mouse old brain w/ a- & g-tocopherol agT-Br-2 |
GSM201813 |
Mouse old brain w/ a- & g-tocopherol agT-Br-3 |
GSM201814 |
Mouse old brain w/ a- & g-tocopherol agT-Br-4 |
GSM201815 |
Mouse old brain w/ a- & g-tocopherol agT-Br-5 |
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This SubSeries is part of SuperSeries: |
GSE8162 |
Age-related transcriptional changes and the effect of dietary supplementation of vitamin E in the mouse heart and brain |
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Relations |
BioProject |
PRJNA105415 |