NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE82143 Query DataSets for GSE82143
Status Public on Sep 01, 2016
Title Differentially expressed genes in certinib-resistant NB-1 xenografts
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary The goal of this study is to elucidate the molecular mechanism that allowed NB-1 xenograft tumors to grow out in the presence of continued ALK inhibition. Poly(A)-selected RNA was extracted from tissues of NB-1 tumors that progressed on ceritinib treatment and those treated with a vehicle to identify differentially expressed genes between these two groups.
 
Overall design mRNA profiles of NB-1 xenograft tumors that progressed on ceritinib treatment and those treated with a vehicle were generated by RNA sequencing, in duplicate, using Illumina HiSeq 2500.
 
Contributor(s) Li F, Ruddy DA, Rakiec DP
Citation(s) 28425916
Submission date Jun 01, 2016
Last update date Sep 02, 2019
Contact name Fang Li
Organization name Novartis Institutes for BioMedical Research, Inc.
Street address 250 Massachusetts Avenue
City Cambridge
State/province MA
ZIP/Postal code 02139
Country USA
 
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (4)
GSM2184217 vehicle-treated 1
GSM2184218 vehicle-treated 2
GSM2184219 relapsed 1
Relations
BioProject PRJNA324126
SRA SRP075983

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE82143_RAW.tar 370.0 Kb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap