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Series GSE8312 Query DataSets for GSE8312
Status Public on Dec 23, 2007
Title Enhancing integrin alpha7 expression effect on myoblast transcription
Organism Mus musculus
Experiment type Expression profiling by array
Summary
Analysis of C2C12 myoblast induced with tetracycline to enhance integrin alpha7 expression. Integrin alpha7 is the major laminin binding integrin in muscle cells. Enhancing its expression has been demonstrated to alleviate pathology in a murine model of Duchenne muscular dystrophy. Results of this study provide insights into the effects of increasing integirn alpha7 expression on muscle cells and possible side effects associate with enhancing integrin alpha7 in muscle cells.
Keywords: comparitive of integrin lapha7 induced and non-induced c2C12 myobalst
 
Overall design Triplicate biological smaples for each condition(induced and non-induced) C2C12 myoblast were used.
 
Contributor(s) Liu J, Kaufman SJ
Citation(s) 18045857
Submission date Jun 27, 2007
Last update date Feb 11, 2019
Contact name Jianming Liu
E-mail(s) liu10@uiuc.edu
Phone 217-333-6058
Fax (217) 244-1648
Organization name University of Illinois at urbana-champaign
Department Department of Cell and Developmental Biology
Lab Dr. Stephen J. Kaufman
Street address B107 CLSL, 601 S. Goodwin Avenue
City Urbana
State/province IL
ZIP/Postal code 61801
Country USA
 
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (6)
GSM206002 Tet integrin alpha7 C2C12 noninduced rep1
GSM206003 Tet integrin alpha7 C2C12 noninduced rep2
GSM206004 Tet integrin alpha7 C2C12 noninduced rep3
Relations
BioProject PRJNA101287

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE8312_RAW.tar 52.9 Mb (http)(custom) TAR (of CEL, CHP, EXP)
Raw data provided as supplementary file
Processed data included within Sample table
Processed data provided as supplementary file

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