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| Status |
Public on Jun 14, 2016 |
| Title |
Expression data of osteogenic differentiated cartilage endplate-derived stem cells (CESCs) under hypoxia or normoxia |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Cartilage endplate-derived stem cells (CESCs) with chondro-osteogenic differentiation capacity may be responsible for the balance of chondrification and ossification in cartilage endplate (CEP). CEP is an avascular and hypoxic tissue, and hypoxia could inhibit the osteogenic differentiation of CESCs.
We used high-throughput scanning to identify differentially expressed genes (DEGs) and alternatively spliced genes (ASGs) during osteogenic differentiation of CESCs under hypoxia compared to those induced under normoxia.
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| Overall design |
Human cartilage endplate-derived stem cells (CESCs) were treated with osteogenic differentiation medium under normoxia and hypoxia for 21 days respectively.
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| Contributor(s) |
Yao Y |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Jun 13, 2016 |
| Last update date |
Oct 29, 2018 |
| Contact name |
Yuan Yao |
| E-mail(s) |
758700974@qq.com
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| Organization name |
Xinqiao Hospital, Third Military Medical University
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| Street address |
83 Xinqiao Street, District of Shapingba
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| City |
Chongqing |
| ZIP/Postal code |
400037 |
| Country |
China |
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| Platforms (1) |
| GPL17586 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
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| Samples (2) |
| GSM2198194 |
CESCs cultured in osteogenic induction medium under hypoxia |
| GSM2198195 |
CESCs cultured in osteogenic induction medium under normoxia |
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| Relations |
| BioProject |
PRJNA325486 |
