|
| Status |
Public on Mar 31, 2020 |
| Title |
SAG/Rbx2-Dependent Neddylation Regulates T-cell Responses |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
We used microarrays to detail the global program of gene expression underlying SAG-dependent neddylation and identified distinct classes of disparate genes during this process.
|
| |
|
| Overall design |
T cells from WT and SAG-deficient (KO) mice were selected for RNA extraction and hybridization on Affymetrix microarrays. We sought to compare the disparate transcripts in naive T cells.
|
| |
|
| Contributor(s) |
Mathewson ND, Reddy P |
| Citation(s) |
27543965 |
| Submission date |
Jun 21, 2016 |
| Last update date |
Mar 31, 2020 |
| Contact name |
Nathan Daniel Mathewson |
| E-mail(s) |
nathand_mathewson@dfci.harvard.edu
|
| Phone |
6176323932
|
| Organization name |
University of Michigan
|
| Department |
Internal Medicine
|
| Lab |
Pavan Reddy
|
| Street address |
1500 E. Medical Center Dr.
|
| City |
Ann Arbor |
| State/province |
MI |
| ZIP/Postal code |
48105 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL16570 |
[MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array [transcript (gene) version] |
|
| Samples (4)
|
| GSM4446985 |
WT_1: Naïve T cells from WT mouse, biological rep1 |
| GSM4446986 |
WT_2: Naïve T cells from WT mouse, biological rep2 |
| GSM4446987 |
KO_3: Naïve T cells from KO mouse, biological rep1 |
| GSM4446988 |
KO_4: Naïve T cells from KO mouse, biological rep2 |
|
| Relations |
| BioProject |
PRJNA622260 |
Less...
More...