|
| Status |
Public on Jul 21, 2016 |
| Title |
Effect of GDF11 on RANKL-induced osteoclastogenesis |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
GDF11 treatment leads to bone loss in mice and strongly stimulates RANKL-induced osteoclastogenesis of bone marrow–derived macrophages (BMMs) in vitro.
We used microarrays to identified distinct classes of up-regulated genes in BMMs after GDF11 treatment.
|
| |
|
| Overall design |
Mouse BMMs were treated with or without GDF11 for RNA extraction and and hybridization on Affymetrix microarrays
|
| |
|
| Contributor(s) |
Liu W, Yuan Q |
| Citation(s) |
27653144 |
| Submission date |
Jul 20, 2016 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Quan Yuan |
| E-mail(s) |
yuanquan@scu.edu.cn
|
| Organization name |
West China Hospital of Stomatology, Sichuan University
|
| Lab |
State Key laboratory of Oral Diseases
|
| Street address |
14 Third section, Renmin Nan Road
|
| City |
Chengdu |
| State/province |
Sichuan |
| ZIP/Postal code |
610041 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA330625 |
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