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| Status |
Public on Sep 08, 2017 |
| Title |
Gene expression of peripheral blood mononuclear cells from adults with sickle cell disease (University of Chicago cohort) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Sickle cell disease is associated with systemic complications, many associated with either severity of disease or increased risk of mortality. We sought to identify a circulating gene expression profile whose predictive capacity spanned the spectrum of these poor outcomes in sickle cell disease.
The Training cohort consisted of patients with SCD who were prospectively recruited from the University of Illinois. The Testing cohort consisted of a combination of patients prospectively seen at two separate institutions including the University of Chicago and Howard University.
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| Overall design |
The gene expression of PBMC from 38 sickle cell disease patients from University of Chicago were analyzed.
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| Contributor(s) |
Lei Z, Desai A, Machado R |
| Citation(s) |
28373264 |
| Submission date |
Jul 20, 2016 |
| Last update date |
Feb 18, 2019 |
| Contact name |
Zhengdeng Lei |
| E-mail(s) |
zlei2@uic.edu
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| Phone |
3123552319
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| Organization name |
University of Illinois at Chicago
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| Department |
Research Resources Center
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| Street address |
1853 W Polk St
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| City |
Chicago |
| State/province |
IL |
| ZIP/Postal code |
60612 |
| Country |
USA |
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| Platforms (1) |
| GPL5175 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [transcript (gene) version] |
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| Samples (38)
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| This SubSeries is part of SuperSeries: |
| GSE84635 |
Gene expression of peripheral blood mononuclear cells from adults with sickle cell disease |
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| Relations |
| BioProject |
PRJNA330709 |
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