|
| Status |
Public on Jan 24, 2008 |
| Title |
In vivo administration of Gamendazole and Lonidamine |
| Platform organism |
Rattus norvegicus |
| Sample organism |
Rattus rattus |
| Experiment type |
Expression profiling by array
|
| Summary |
rat testis time changes
Experimental details are found at Tash et al, Gamendazole, an orally active indazole carboxylic acid male contraceptive agent, targets HSP-90, eEF1A, and stimulates IL-1 transcription in Sertoli cells, Biol. Reprod. (2007) under review
Keywords: time course
|
| |
|
| Overall design |
Adult male rats administered single ip dose of 6mg/kg Gamendazole or 25 mg/kg lonidamine or vehicle control (buffered DMSO) - testes harvested at 0 4 12 and 24 hr - 3 chips used for each time point
|
| |
|
| Contributor(s) |
Tash JS |
| Citation(s) |
18218612 |
| Submission date |
Jul 16, 2007 |
| Last update date |
Jul 31, 2017 |
| Contact name |
Joseph S Tash |
| E-mail(s) |
jtash@kumc.edu
|
| Phone |
913-588-7421
|
| Fax |
913-588-7180
|
| Organization name |
University of Kansas Medical Center
|
| Department |
Center for Male Contraceptive Research and Drug Development
|
| Street address |
3901 Rainbow Blvd.
|
| City |
Kansas City |
| State/province |
KS |
| ZIP/Postal code |
66160 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL1355 |
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array |
|
| Samples (10)
|
|
| Relations |
| BioProject |
PRJNA101575 |
Less...
More...